(2025) explore CAR-T cell therapy, a cancer-derived treatment now being tested for autoimmune diseases like lupus.
This experimental approach uses genetically modified immune cells to target malfunctioning immune responses, potentially resetting the system.
The review highlights its application in rheumatic diseases, suggesting it could achieve long-term remission by addressing autoimmune root causes rather than symptom management.
While still in early research phases, CAR-T therapy represents a precision medicine shift for lupus.
The authors emphasize its potential to reduce dependence on traditional immunosuppressants with significant side effects.
However, more studies are needed to confirm safety and efficacy in autoimmune contexts before clinical adoption (Patil et al., 2025).
Clinical Trials
This is a list of upcoming or ongoing clinical trials that are actively recruiting and have been listed or updated in the last two weeks:
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