Systemic Lupus Erythematosus Insights

A recent study highlights the potential of a new...

April 09, 2025 • Estimated Reading Time: 1 minute

Latest Research

A recent study highlights the potential of a new IgD-FcδR blocker, an IgD-Fc-Ig fusion protein, in treating systemic lupus erythematosus (SLE). This innovative treatment aims to reduce the abnormal activation of T cells, which play a significant role in the disease's progression. Elevated IgD levels have been observed in SLE patients, suggesting a link between this immunoglobulin and the disease's pathogenesis.

Targeting these pathways may provide a novel therapeutic approach for managing SLE symptoms and improving patient outcomes. This could represent a significant advancement in SLE management, offering hope for more effective interventions in the future (He et al., 2025).

Clinical Trials

This is a list of upcoming or ongoing clinical trials that are actively recruiting and have been listed or updated in the last two weeks:

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies

A Study of Felzartamab in Participants With Lupus Nephritis

Study of Systemic Lupus Erythematosus

A Treatment Effectiveness Study Among SLE Patients Receiving Anifrolumab in Routine Clinical Practice

View the full list of clinical trials →

Community News

Lupus TrustApr 03, 2025

This is definitely me! 🙄

Lupus Research AllianceApr 07, 2025

🌍 On #WorldHealthDay, let's spread #LupusAwareness. The cause of lupus remains unknown, but there is solid evidence that genetics, epigenetics (changes in chromosomes that affect gene activity), environmental factors, viruses and infections play a role. Learn more about #lupus symptoms, treatments, and more: https://bit.ly/aboutlupus

Goodbye Lupus by Brooke Goldner, M.D.Apr 03, 2025

THROWBACK THURSDAY - This was the inspiration for my book Goodbye Autoimmune Disease, to help people overcome the emotional and psychological events and barriers holding them back from their health

In my appointments and programs, this is the greatest focus for how I help people, the diet is the easy part!

Chronic illness can create emotional trauma, and trauma can create chronic illness because it is directly inflammatory. Healing your spirit is an important part of healing your chronic disease in addition to using my nutrition protocol to reverse your disease. Healing is a physical and emotional experience! That is why so much of my new book Goodbye Autoimmune Disease centers around healing psychological barriers, sabotage, anxiety, beliefs, and habits keeping people sick, because those things will keep you sick even with the best nutrition. If you’ve already read my book, let me know in the comments which chapters helped you the most.